American Thoracic Society Documents An Official American Thoracic Society/European Respiratory Society Statement: Asthma Control and Exacerbations Standardizing Endpoints for Clinical Asthma Trials and Clinical Practice
نویسندگان
چکیده
Helen K. Reddel, D. Robin Taylor, Eric D. Bateman, Louis-Philippe Boulet, Homer A. Boushey, William W. Busse, Thomas B. Casale, Pascal Chanez, Paul L. Enright, Peter G. Gibson, Johan C. de Jongste, Huib A. M. Kerstjens, Stephen C. Lazarus, Mark L. Levy, Paul M. O’Byrne, Martyn R. Partridge, Ian D. Pavord, Malcolm R. Sears, Peter J. Sterk, Stuart W. Stoloff, Sean D. Sullivan, Stanley J. Szefler, Mike D. Thomas, and Sally E. Wenzel, on behalf of the American Thoracic Society/European Respiratory Society Task Force on Asthma Control and Exacerbations
منابع مشابه
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice.
BACKGROUND The assessment of asthma control is pivotal to the evaluation of treatment response in individuals and in clinical trials. Previously, asthma control, severity, and exacerbations were defined and assessed in many different ways. PURPOSE The Task Force was established to provide recommendations about standardization of outcomes relating to asthma control, severity, and exacerbations...
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rejection after lung transplantation. Eur Respir J 2011; 37: 164–172. 6 Sutherland ER, King TS, Icitovic N, et al. A trial of clarithromycin for the treatment of suboptimally controlled asthma. J Allergy Clin Immunol 2010; 126: 747–753. 7 Brusselle GG, Vanderstichele C, Jordens P, et al. Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-bli...
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References 1 Dias-Júnior SA, Reis M, de Carvalho-Pinto RM, et al. Effects of weight loss on asthma control in obese patients with severe asthma. Eur Respir J 2014; 43: 1368–1377. 2 Bland JM, Altman DG. Comparisons against baseline within randomised groups are often used and can be highly misleading. Trials 2011; 12: 264. 3 Diggle PJ, Heagerty PJ, Liang K, et al. Analysis of Longitudinal Data. 2...
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Acute exacerbations of asthma and chronic obstructive pulmonary disease (COPD) are the major cause of morbidity, mortality, and health costs of both diseases. Currently available treatments are poorly effective in both acute treatment of and prevention of acute exacerbations. New treatments for intervention and prophylaxis are therefore required; to facilitate their development, we must underst...
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